Microfluidics Core Facility Microfabrication of Devices for cell migration

We offer fabrication services of devices for cell migration. Using photolithography allows us to generate paths and obstacles for cells to migrate through, around or even above.  The image shows channels bridging two reservoirs. The channels have a height of around 10µm, while the reservoirs are 200µm high. This allows the cells to attach in the reservoirs and forces them to migrate through narrow spaces. The cells can be later collected or analyzed directly on chip. This is again just an exemplary device; the channels and reservoirs can be altered in shape, geometry and dimensions, making this a powerful tool for cell analysis. Besides cell migration, these structures can also be used to investigate cell-cell communication or other relevant questions. These are just examples for applications.