AG Selhuber-Unkel Research 3D Biomaterials
3D Biomaterial fabrication in the micrometer range based on Direct-Laser Writing
We are using a commercially available direct laser writing (DLW) setup (Nanoscribe Photonic Professional GT2) based on two-photon polymerization. A focused femtosecond pulsed near-infrared (NIR) laser (λ = 780 nm) is focused on a substrate to initiate the polymerization reaction of a photosensitive resin in a very small volume (<1 μm3). Using two-photon polymerization microstructures can be fabricated with great flexibility benefitting from a high freedom in 3D designs and high resolution in the (sub)-micrometer range. To fabricate our biomaterials of choice, we are using commercially available bio inks as well as custom-made resins. Different members of our group work on different 3D Biomaterials using the two-photon polymerization DLW approach.
Responsible scientists
- Gaurav Dave
- Dr. Barbara Schamberger
- Målin Schmidt
- Annabelle Sonn
- Dr. Mohammadreza Taale (former)
Funding
Publications
- M. Taale, B. Schamberger, M. A. Monclus, C. Dolle, F. Taheri, D. Mager, Y. M. Eggeler, J. G. Korvink, J. M. Molina-Aldareguia, C. Selhuber-Unkel, A. D. Lantada, M. Islam. “Microarchitected Compliant Scaffolds of Pyrolytic Carbon for 3D Muscle Cell Growth”. Adv. Healthcare Mater. 2024, 13, 2303485.
- T. Spratte, S. Geiger, F. Colombo, A. Mishra, M. Taale, L.-Y. Hsu, E. Blasco, C. Selhuber-Unkel. “Increasing the Efficiency of Thermoresponsive Actuation at the Microscale by Direct Laser Writing of pNIPAM”. Adv. Mater. Technol. 2023, 8, 2200714.
Cluster of Excellence 3D Matter Made to Order
In the Cluster of Excellence “3D Matter Made to Order” (3DMM2O) we are exploring direct laser writing for 3D structuring biomaterials. Our main applications are in the fields of controlling cell growth in 3D.
